Manufactured By: Thermo Fisher Scientific

Thermo Scientific PHARMA HME

The Thermo Scientific PHARMA HME is ideal for small-scale continuous processing in research, development or production in the pharmaceutical industry.

The stainless steel extruders are built to GMP standards with a focus on a clean, streamlined design

Comprehensive Range of Capabilities
Available in 16 mm and 24 mm sizes, the Thermo Scientific PHARMA HME series is complemented by a full range of ancillary equipment for product mixing, and postextrusion processing.

Designed for Pharmaceutical Needs
The horizontally split barrels (up to 40:1 L/D) have a crevice-free, GMP design. Quick release clamps give easy access to screws and process contact surfaces for cleaning or configuration changes. Both barrel liners and the screws themselves can be easily removed for cleaning or product changeover. The barrel is modular, with interchangeable segments for feeding solids and liquids, or for venting. The variable speed AC motors are brushless and therefore low maintenance.

The touch-screen display is easy to use and easy to clean. The PLC incorporates data acquisition with an option to download to a remote computer for archiving and analysis. The controls include recipe storage of preset extruder parameters for repeatable process conditions.

Ancillary Equipment
We offer a range of ancillary equipment to integrate with our twin-screw extruders, including pre-mixers, feeders, chill rolls, air-cooled conveyors, pelletizers, and cast sheet or blown film lines. GMP standard pharmaceutical versions of the ancillaries are available with stainless steel construction and dust-tight touch-screen operator interface where applicable.

• Reduced clean room area
• Consistent, controllable processing
• Suitable for PAT
• Reduced product changeover time
• On-demand production
• Minimized scale-up risk
• Reliable cleaning

• Medical polymers
• Drug delivery systems
• Soft gels

• Melt granulation
• Biomedical compounds
• Water sensitive products
• Medical adhesives

• Small footprint
• Continuous operation
• High free volume
• Small process inventory
• Segmented screws and barrel
• Removable screws and liners

Additional Product Information:

Item Size Download
Product Brochure 172kb Download
Product Specifications 346kb Download

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